Applications of toxicogenomics in safety evaluation and risk assessment (Record no. 129944)
| 000 -LEADER | |
|---|---|
| fixed length control field | 02784nam a2200385 a 4500 |
| 082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 616/.042 |
| 245 00 - TITLE STATEMENT | |
| Title | Applications of toxicogenomics in safety evaluation and risk assessment |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Place of publication | Hoboken, N.J. : |
| Name of publisher | John Wiley & Sons, |
| Year of publication | c2011. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | xiii, 377 p., [8] p. of plates : |
| Other physical details | ill. (some col.) |
| 505 0# - FORMATTED CONTENTS NOTE | |
| Formatted contents note | Toxicology, "omics" technologies, and toxicogenomics : a primer -- Introduction to human health risk assessment -- Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward -- Approaches and practical considerations for the analysis of toxicogenomics data -- Genomics in identifying mutagenic mode of action in carcinogenesis -- Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens -- Genomics in characterizing endocrine toxicity -- Studying organ specific toxicity using gene expression profiling -- Toxicogenomic studies in human populations -- Toxicogenomics applied to ecological risk assessment -- Analysis of transcriptomic dose response data for toxicology and risk assessment -- Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges -- Toxicogenomics and animal alternatives -- Toxicogenomics and the regulatory framework -- Standardization of gene expression information for the safety evaluation--activities in Japan - -- Applying transcriptional profiling in drug safety evaluation -- Reframing the risk assessment paradigm : towards a systems biology approach. |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Genetic toxicology. |
| Topical Term | Toxicity testing. |
| Topical Term | Health risk assessment. |
| 700 1# - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Boverhof, Darrell R. |
| Personal name | Gollapudi, B. Bhaskar. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS | |
| Uniform Resource Identifier | http://site.ebrary.com/lib/rucke/Doc?id=10494674 |
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