High-throughput screening methods in toxicity testing (Record no. 171786)

000 -LEADER
fixed length control field 02294nam a2200337 a 4500
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 615.1/9
245 00 - TITLE STATEMENT
Title High-throughput screening methods in toxicity testing
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication Hoboken, N.J. :
Name of publisher Wiley,
Year of publication 2013.
300 ## - PHYSICAL DESCRIPTION
Number of Pages xv, 552 p., [16] p. of plates :
Other physical details ill. (some col.)
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note pt. 1. General aspects -- pt. 2. High-throughput assays to assess different cytotoxicity endpoints -- pt. 3. High-throughput assays to assess DNA damage and carcinogenesis -- pt. 4. High-throughput assays to assess reproductive toxicity, cardiotoxicity, and haematotoxicity -- pt. 5. High-throughput assays to assess drug metabolism and receptor-related toxicity.
520 ## - SUMMARY, ETC.
Summary, etc "High-throughput assays are part of a paradigm shift, to more cost-effective and reliable methods, in the testing of chemical and drug safety. This book covers methods, data generation, data analysis, and applications in risk assessment for major toxicological assays to help toxicologists apply and understand the benefits and limits of high-throughput testing assays. Each chapter describes method principles and includes detailed information on data generation, data analysis, and applications in risk assessment. The topic is especially timely given Europe's REACH legislation and the US National Research Council"--
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term High throughput screening (Drug development)
Topical Term Toxicity testing.
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Steinberg, Pablo.
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier http://site.ebrary.com/lib/rucke/Doc?id=10662545
520 ## - SUMMARY, ETC.
-- Provided by publisher.

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