Resolving erroneous reports in toxicology and therapeutic drug monitoring

by Dasgupta, Amitava,
Additional authors: ebrary, Inc.
Published by : John Wiley & Sons, (Hoboken, N.J. :) Physical details: viii, 457 p. : ill. Year: 2012
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Includes bibliographical references and index.

An introduction to tests performed in toxicology laboratories and methodologies available for such testings -- Challenges in drugs of abuse testing -- False positive results in immunoassays for drugs of abuse testing -- True positive drugs of abuse test results due to prescription and non-prescription drugs -- When toxicology report is negative in a suspected overdosed patient : the world of designer drugs -- Abuse of magic mushroom, peyote cactus and solvent : no readily available laboratory tests -- False positive alcohol tests using breath analyzers and automated analyzers -- Role of laboratory in detecting other poisoning including pesticides, ethylene glycol, and methanol -- Poisoning with warfarin and superwarfarin : what laboratory can do? -- Plant poisoning and clinical laboratory -- Sources of erroneous results in therapeutic drug monitoring due to pre-analytical errors, high bilirubin, hemolysis, and heterophilic antibody -- Interferences in immunoassays used for digoxin monitoring -- Interferences in immunoassays used for monitoring anticonvulsants and usefulness of monitoring free anticonvulsants in certain patients -- Interferences in immunoassays used for monitoring tricyclic antidepressant -- Therapeutic drug monitoring of immunosuppressant drugs : limitations of immunoassays and need for chromatographic methods -- Effect of drug-herb interactions on therapeutic drug monitoring -- Pharmacogenomics and toxicology laboratory -- Approaches for eliminating interference/discordant specimen in therapeutic drug monitoring and drugs of abuse testing.

Electronic reproduction. Palo Alto, Calif. : ebrary, 2011. Available via World Wide Web. Access may be limited to ebrary affiliated libraries.

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